Apollo Scientific Verapamil Hydrochloride

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Specifications:
Application cell Signalling
Storage Temperature 2-8°C
Product Type Laboratory Chemical Forms Powder
Product Brand Apollo Scientific
Product Grade Molecular Biology Formula C₂₇H₃₈N₂O₄

Apollo Scientific Verapamil Hydrochloride is a high-purity calcium channel blocker used as a pharmaceutical reference standard and biochemical research compound. It functions by inhibiting calcium ion influx through slow calcium channels, reducing myocardial contractility and vascular tone.

This compound is widely utilized in cardiovascular pharmacology research, particularly in studies involving hypertension, angina pectoris, arrhythmia, and smooth muscle relaxation. It is also applied in drug metabolism, receptor binding assays, and analytical method development.

Chemical Information

PropertyDetails
Chemical NameVerapamil Hydrochloride
Synonyms5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride; Verapamil HCl; (±)-Verapamil hydrochloride
Chemical FormulaC₂₇H₃₈N₂O₄·HCl
Molecular Weight491.07 g/mol
CAS Number152-11-4
MDL NumberMFCD00055208
EINECS205-800-5
UN Number2811
ADR Classification6.1, III (Toxic Substance)
Storage TemperatureRefrigerator (2–8 °C)
Hazard ClassificationToxic

Physical and Chemical Properties

PropertyValue
AppearanceWhite to off-white crystalline powder
Purity (Assay)Typically ≥98% (pharmaceutical grade)
SolubilityFreely soluble in water and ethanol
StabilityStable under recommended storage conditions
OdorOdorless
Melting Point140–145 °C (approx.)
GradeAnalytical / Pharmaceutical Reference Standard

Applications

  • Pharmacological research on calcium channel modulation.
  • Reference standard for HPLC, LC-MS, and analytical quality control.
  • Cardiovascular studies involving myocardial contractility and vasodilation.
  • In vitro and in vivo assays on cardiac and smooth muscle tissues.
  • Toxicological and drug interaction research.
  • Education and pharmaceutical development studies.

Safety and Handling

Hazard Classification: Toxic

Hazard Statements:

  • Toxic if swallowed, inhaled, or absorbed through skin.
  • Causes damage to organs through prolonged or repeated exposure.

Precautions:

  • Use gloves, protective eyewear, and laboratory coat.
  • Handle only in a chemical fume hood.
  • Avoid contact with skin, eyes, and clothing.
  • Dispose of waste according to local hazardous chemical regulations.

Storage:

  • Store refrigerated (2–8 °C) in a tightly closed container.
  • Protect from moisture and light.

Packaging and Ordering Information

Catalog NumberPackaging TypePack SizeContainer
BIV1326-5GBottle5 gAmber glass bottle
BIV1326-25GBottle25 gAmber glass bottle


Apollo Scientific Verapamil Hydrochloride is a toxic, high-purity calcium channel blocker widely used in pharmacological, biochemical, and analytical research. It serves as a reliable reference compound for cardiovascular drug studies, receptor binding assays, and quality control in pharmaceutical analysis, ensuring precision and reproducibility in laboratory results.

  • Pack Size:   5g 25g
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