Specifications:
| Application | Cell culture | ||
| Storage Temperature | -20°C | ||
| Product Type | Antifungals | Forms | Powder |
| Product Brand | Apollo Scientific | ||
| Product Grade | Microbiology grade | Formula | C₅₈H₇₃N₇O₁₇ |
Apollo Scientific™ Anidulafungin is a high-purity, semisynthetic echinocandin antifungal compound widely used in antifungal susceptibility testing, resistance studies, and pharmaceutical research. It is commonly employed as an internal positive inhibitor control in minimum inhibitory concentration (MIC) assays and as a reference compound in disk diffusion assays for evaluating antifungal drug resistance and tolerance in Candida species.
Anidulafungin exerts its antifungal activity by inhibiting β-(1,3)-D-glucan synthase, an enzyme essential for fungal cell wall synthesis and absent in mammalian cells, resulting in selective antifungal activity.
Key Features
- High Purity (≥98%) – Suitable for advanced pharmaceutical and microbiological research
- Echinocandin-Class Antifungal – Distinct from azoles and polyenes
- Selective Mechanism of Action – Targets fungal cell wall synthesis
- Ideal Positive Control – Commonly used in MIC and disk diffusion assays
- Well-Characterized Reference Compound – Extensively cited in antifungal research
- Available in Precise Milligram Quantities – Optimized for high-value assays
Biochemical & Pharmacological Action
Anidulafungin is a semisynthetic echinocandin featuring an alkoxytriphenyl side chain, which contributes to its potent antifungal activity. It inhibits β-(1,3)-D-glucan synthase, leading to disruption of fungal cell wall integrity and cell death.
This mechanism underpins its therapeutic relevance in oesophageal and invasive candidiasis, and its widespread use as a benchmark antifungal agent in susceptibility testing.
Chemical & Technical Information
| Parameter | Specification |
|---|---|
| Chemical Name | Anidulafungin |
| CAS Number | 166663-25-8 |
| Molecular Class | Echinocandin antifungal |
| Purity | ≥98% |
| Mechanism | β-(1,3)-D-glucan synthase inhibition |
| Physical Form | Solid |
| Application Area | Antifungal research & AST |
Available Pack Sizes
| Pack Size | Product Code |
|---|---|
| 5 mg | BUP13095-5MG |
| 10 mg | BUP13095-10MG |
| 25 mg | BUP13095-25MG |
| 50 mg | BUP13095-50MG |
| 100 mg | BUP13095-100MG |
| 200 mg | BUP13095-200MG |
Applications
- Antifungal minimum inhibitory concentration (MIC) assays
- Internal positive inhibitor control in AST
- Disk diffusion assays for antifungal resistance studies
- Candida drug resistance and tolerance research
- Mechanistic studies of fungal cell wall synthesis
Apollo Scientific™ Anidulafungin (≥98% purity) is a high-quality, research-grade echinocandin antifungal ideal for MIC testing, antifungal susceptibility studies, and resistance research. Its selective mechanism of action, reproducible performance, and availability in precise milligram quantities make it an essential reference compound for clinical, academic, and pharmaceutical laboratories.
- Pack Size: 10mg 5mg 25mg 200mg 50 mg 100 mg
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