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Accuris SmartDrop™ Nano Spectrophotometers for Microvolume Analysis of DNA, RNA and Proteins
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Specifications:
| Application | molecular biology, Spectrophotometry | Warranty | 1 Year |
| Storage Temperature | Ambient | ||
| Product Type | Molecular Biology Equipment | ||
| Product Brand | Accuris Instruments | ||
The Accuris SmartDrop™ series of nano spectrophotometers delivers fast, accurate quantification of nucleic acids and proteins from extremely small sample volumes. By using only a tiny droplet of sample, SmartDrop instruments eliminate the need for dilution in many workflows, helping laboratories achieve more reliable concentration and purity measurements while conserving valuable samples.
Designed for speed and convenience, each SmartDrop model features a 7-inch full-color touchscreen, intuitive icon-based menus, and preprogrammed methods that allow users to begin measurements immediately without requiring an external computer or additional software. Samples are applied directly onto the quartz pedestal, where the instrument forms a precise liquid column for absorbance analysis. Within seconds, DNA, RNA, and protein concentration results, along with purity ratios, are displayed clearly on screen.
To support everyday molecular biology and microbiology workflows, all SmartDrop models include an integrated printer, USB data export, onboard memory storage, and a built-in cuvette port for OD600 measurements. For laboratories requiring even greater sensitivity, the SmartDrop XF combines full-spectrum UV-Vis spectrophotometry with integrated fluorescence detection for low-concentration nucleic acid quantification.
Key Features
- Rapid quantification of DNA, RNA, and proteins from microvolume samples
- Requires as little as 0.5 µl of sample, depending on model
- No external PC or software required
- Large 7-inch touchscreen with user-friendly menu navigation
- Integrated printer for immediate result documentation
- USB export of data as Excel files
- Built-in cuvette port for OD600 readings
- Quartz pedestal for direct droplet measurement
- Models available for basic absorbance, full-spectrum UV-Vis, or UV-Vis plus fluorescence
- SmartDrop XF supports sensitive quantification with fluorescence dyes such as PicoGreen, RiboGreen, GFP, and fluorescein
Product Range Overview
SmartDrop L (NS1000)
The SmartDrop L is an economical solution for laboratories performing routine DNA, RNA, and protein quantification. It uses LED and silicon detector technology to measure absorbance at 260 and 280 nm, automatically calculating the 260/280 purity ratio. With a fixed 0.5 mm path length, it is ideal for users who need reliable basic nucleic acid and protein analysis at an affordable price point.
SmartDrop X (NS1010)
The SmartDrop X is a full-spectrum UV-Vis nano spectrophotometer designed for more advanced analytical applications. It scans across 200 to 800 nm, allowing users to evaluate nucleic acids, proteins, and unknown samples, while also supporting colorimetric assays such as BCA, Bradford, and Lowry. Its auto-ranging path lengths of 0.2 mm and 1.0 mm improve measurement accuracy across a wider concentration range.
SmartDrop XF (NS1020)
The SmartDrop XF is the most advanced model in the series, combining full-spectrum absorbance with an integrated fluorometer for highly sensitive nucleic acid quantification. Featuring three auto-ranging path lengths and fluorescence capability, it is well suited for applications involving low-concentration DNA or RNA samples where absorbance alone may not provide sufficient sensitivity or selectivity.
Applications
- DNA quantification
- RNA quantification
- Protein concentration measurement
- Nucleic acid purity assessment
- OD600 bacterial culture measurements
- Full-spectrum absorbance analysis
- Colorimetric protein assays
- Low-concentration nucleic acid fluorescence quantification
- Molecular biology, genomics, proteomics, and microbiology workflows
Technical Specifications
| Specification | SmartDrop L (NS1000) | SmartDrop X (NS1010) | SmartDrop XF (NS1020) |
|---|---|---|---|
| Display | 7-inch touch screen | 7-inch touch screen | 7-inch touch screen |
| Minimum Sample Size | 1.0–2.0 µl | 0.5–2.0 µl | 0.5–2.0 µl |
| Path Length | 0.5 mm | 0.2 mm, 1.0 mm | 0.05 mm, 0.2 mm, 1.0 mm |
| Light Source | UV LED | Xenon Flash Lamp | Xenon Flash Lamp |
| Detector | UV Silicon Photocell | 2048 Element Linear Silicon CCD Array | 2048 Element Linear Silicon CCD Array |
| Wavelength Range | 260, 280, 600 nm | 200–800 nm | 200–800 nm |
| Absorbance Range | 0.2–50 A | 0.04–90 A | 0.04–300 A |
| Absorbance Precision | 0.005 A | 0.003 A | 0.003 A |
| Lower Detection Limit | dsDNA: 10 ng/µl; BSA: 0.5 mg/ml | dsDNA: 2 ng/µl; BSA: 0.1 mg/ml | dsDNA: 2 ng/µl; BSA: 0.1 mg/ml |
| Upper Detection Limit | dsDNA: 2,500 ng/µl; BSA: 75 mg/ml | dsDNA: 4,500 ng/µl; BSA: 135 mg/ml | dsDNA: 15,000 ng/µl; BSA: 450 mg/ml |
| Detection Time | < 6 seconds | < 5 seconds | < 6 seconds |
| Communication Ports | USB | USB | USB |
| Voltage Input | DC 24V, 2A | DC 24V, 2A | DC 24V, 2A |
| Power | 25W | 25W | 25W |
| Dimensions (W × D × H) | 20.8 × 28.0 × 18.6 cm | 20.8 × 28.0 × 18.6 cm | 20.8 × 32.0 × 18.6 cm |
| Weight | 3.6 kg | 3.6 kg | 3.6 kg |
Cuvette OD600 Detection Specifications
| Parameter | SmartDrop L | SmartDrop X | SmartDrop XF |
|---|---|---|---|
| Absorbance Range | 0.0–4.0 A | 0.0–4.0 A | 0.0–4.0 A |
| Absorbance Stability | [0,3) ≤ 0.5%, [3,4) ≤ 2% | [0,3) ≤ 0.5%, [3,4) ≤ 2% | [0,3) ≤ 0.5%, [3,4) ≤ 2% |
| Absorbance Repeatability | [0,3) ≤ 0.5%, [3,4) ≤ 2% | [0,3) ≤ 0.5%, [3,4) ≤ 2% | [0,3) ≤ 0.5%, [3,4) ≤ 2% |
| Absorbance Precision | [0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2% | [0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2% | [0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2% |
Fluorescence Detection Specifications
| Parameter | SmartDrop XF |
|---|---|
| Excitation / Emission | 460 ± 20 nm / 525–570 nm |
| Sensitivity | dsDNA: 0.5 pg/µl |
| Linearity | R² ≥ 0.995 |
| Repeatability | ≤ 1.5% |
| Stability | ≤ 1.5% |
Related Accessories
- NS1020-T Fluorescence Detection Tubes, 0.5 mL, pack of 250
- Optical glass cuvettes for OD600 measurement
- Accuris DNA Quantification Kits for dsDNA, ssDNA, and RNA
Comparison Summary
| Model | Best For | Main Advantage |
|---|---|---|
| SmartDrop L | Routine DNA/RNA/protein checks | Affordable and simple operation |
| SmartDrop X | Advanced absorbance and full-spectrum analysis | Broad wavelength scanning and assay flexibility |
| SmartDrop XF | High-sensitivity nucleic acid work | Combines UV-Vis spectrophotometry with fluorescence detection |
Unique Advantages
- Minimal sample requirement helps preserve precious samples
- Standalone operation reduces setup complexity
- Fast measurement times improve laboratory efficiency
- Integrated printer and USB export simplify record keeping
- OD600 cuvette capability adds microbiology workflow value
- SmartDrop XF provides both broad dynamic range and high-sensitivity fluorescence detection in one instrument
The Accuris SmartDrop™ Nano Spectrophotometer series offers a flexible solution for laboratories requiring fast, convenient, and accurate microvolume analysis. Whether the need is for economical routine quantification, full-spectrum UV-Vis analysis, or sensitive fluorescence-based nucleic acid measurement, the SmartDrop L, X, and XF models provide options tailored to different laboratory applications and budgets.
- Model: SmartDrop™ L SmartDrop™ X SmartDrop™ XF