Specifications:
| Application | Organic Synthesis | ||
| Storage Temperature | Ambient | ||
| Product Type | Laboratory Chemical | Forms | Powder |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Analytical grade | Formula | C₉H₇N |
Thermo Scientific™ Quinoline, ≥98% is a high-purity aromatic nitrogen heterocycle used extensively in organic synthesis, pharmaceutical development, and coordination chemistry. Quinoline serves as a versatile intermediate in the synthesis of a variety of antimicrobial, antimalarial, and anticancer agents, as well as ligands for metal complexes. Its fused aromatic ring structure, consisting of a benzene ring fused to a pyridine ring, provides unique reactivity for advanced synthetic applications.
Key Features
- High Purity (≥98%) – Suitable for synthesis, R&D, and analytical purposes
- Versatile Synthetic Intermediate – Precursor to quinoline-based pharmaceuticals and ligands
- Aromatic Nitrogen Heterocycle – Fused benzene-pyridine ring system with enhanced chemical reactivity
- Available in Multiple Pack Sizes – Ideal for lab-scale to pilot-scale synthesis
Chemical & Physical Properties
| Property | Specification |
|---|---|
| Chemical Name | Quinoline |
| CAS Number | 91-22-5 |
| Chemical Formula | C₉H₇N |
| Molecular Weight | 129.16 g/mol |
| Purity | ≥98% |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 237 °C |
| Melting Point | –15 °C |
| Density | 1.090 g/cm³ (20 °C) |
| Flash Point | 101 °C (214 °F) |
| Storage Conditions | Ambient |
| EINECS Number | 202-051-6 |
| Merck Index | 14,8068 |
| MDL Number | MFCD00006736 |
| UN Number | UN2656 |
| ADR Classification | Class 6.1 (Toxic), Packing Group III |
| Hazard Symbols | GHS06 (Toxic), GHS08 (Health hazard), GHS07 (Irritant) |
Applications
- Organic Synthesis – Intermediate in the synthesis of antimalarial drugs (e.g., chloroquine derivatives), antifungals, and dyes
- Pharmaceutical Chemistry – Building block for heterocyclic drug scaffolds
- Coordination Chemistry – Ligand for transition metal complexes in catalysis and materials science
- Analytical Chemistry – Used in fluorescence-based assays and trace metal detection
- Research & Development – Ideal for reaction mechanism studies and compound library synthesis
Safety & Handling
- Hazard Classification: Toxic if swallowed or inhaled; may cause organ damage with prolonged exposure
- Precautions: Use in a chemical fume hood; wear appropriate PPE (gloves, goggles, lab coat)
- Storage: Store in tightly sealed containers at room temperature, away from heat and oxidizing agents
Ordering Information
| Catalog # | Pack Type | Quantity |
|---|---|---|
| 43225.18 | Glass bottle (solids) | 50 g |
| 43225.30 | Glass bottle (solids) | 250 g |
| 43225.A1 | Glass bottle (solids) | 1 kg |
Thermo Scientific™ Quinoline, ≥98%, is a reliable, high-purity chemical essential for advanced synthetic and pharmaceutical chemistry. Its broad utility as a heterocyclic scaffold and intermediate makes it a valuable compound for academic, industrial, and R&D laboratories.
- Pack Size: 250g 1kg 50g
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