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Thermo Scientific™ NanoDrop™ Lite Plus Microvolume Spectrophotometer
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Specifications:
| Application | Nucleic Acid Quantitation | Warranty | 1 Year |
| Storage Temperature | Room Temperature | ||
| Product Type | Laboratory Equipment | ||
| Product Brand | Thermo Fisher Scientific™ | ||
| Product Grade | Molecular Biology | ||
The Thermo Scientific™ NanoDrop™ Lite Plus Spectrophotometer is a compact, entry-level microvolume UV-Vis spectrophotometer designed for rapid and accurate quantification of DNA, RNA, and protein samples. Built on the trusted NanoDrop technology platform, this instrument enables precise concentration measurement and purity assessment using only 1–2 μL of sample, eliminating the need for cuvettes or costly consumables.
The NanoDrop Lite Plus provides reliable nucleic acid and protein quantification with built-in purity ratio analysis (A260/A280 and A260/A230), making it an ideal solution for academic laboratories, teaching environments, and routine molecular biology workflows. Its standalone operation, intuitive touchscreen interface, and compact design make it easy to use in any laboratory setting.
Key Features
Microvolume Sample Measurement
- Requires only 1–2 μL sample volume
- No cuvettes, capillaries, or consumables required
- Ideal for precious or limited samples
Fast and Accurate Quantification
- Measurement time of ≤ 5 seconds
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Quantifies:
- DNA up to 1,500 ng/μL
- RNA up to 1,200 ng/μL
- Protein up to 45 mg/mL
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Detection limits as low as:
- 2 ng/μL dsDNA
- 1.6 ng/μL RNA
Purity Assessment for Sample Quality Control
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Calculates key purity ratios:
- A260/A280 (protein contamination)
- A260/A230 (organic contamination)
- Ensures sample suitability for downstream applications
Sample Retention Technology
- Surface tension holds sample on measurement pedestal
- No sample dilution required
- Easy sample loading and cleanup
Standalone Operation and Data Storage
- Built-in touchscreen interface
- No external computer required
- Stores up to 1,000 measurements
- USB export capability for data transfer
Compact and User-Friendly Design
- Small footprint ideal for crowded laboratory benches
- Durable stainless steel and quartz optical components
- Easy-to-use interface for fast training and operation
Applications
The NanoDrop Lite Plus Spectrophotometer is ideal for:
- DNA quantification workflows
- RNA quantification workflows
- Protein concentration measurement
- PCR and qPCR sample preparation
- Next-generation sequencing (NGS) sample quality control
- Molecular biology research
- Academic teaching laboratories
- Biotechnology and research laboratories
Advantages Over Traditional Spectrophotometers
- No cuvettes or consumables required
- Minimal sample volume requirement
- Faster measurement time
- Easy operation with standalone interface
- Compact and portable design
Technical Specifications
| Parameter | Specification |
|---|---|
| Sample Volume | 1–2 μL |
| Measurement Time | ≤ 5 seconds |
| Absorbance Range | 0.04–30 Abs |
| Wavelength Range | 230, 260, 280 nm |
| DNA Quantification Range | Up to 1,500 ng/μL |
| RNA Quantification Range | Up to 1,200 ng/μL |
| Protein Quantification Range | Up to 45 mg/mL |
| Detection Limits | 2 ng/μL dsDNA, 1.6 ng/μL RNA |
| Pathlength | 0.2 mm and 1.0 mm (auto-adjust) |
| Light Source | Xenon Flash Lamp |
| Detector | CMOS Linear Image Sensor |
| Display | LCD Touchscreen |
| Data Export | USB |
| Dimensions | 27 × 22 × 22 cm |
| Weight | 2.7 kg |
| Warranty | 2 Years |
Ideal Users
- Academic teaching laboratories
- Research laboratories
- Biotechnology startups
- Molecular biology laboratories
- Genomics laboratories
Comparison with Qubit Fluorometers
| Feature | NanoDrop Lite Plus | Qubit Fluorometer |
|---|---|---|
| Measurement Method | UV absorbance | Fluorescence |
| Sample Volume | 1–2 μL | 1–20 μL |
| Sensitivity | Moderate | Very high |
| Measures Purity Ratios | Yes | No |
| Accuracy at Low Concentrations | Moderate | Excellent |
NanoDrop is ideal for rapid purity checks, while Qubit provides higher accuracy for sequencing workflows.
The Thermo Scientific™ NanoDrop™ Lite Plus Spectrophotometer provides fast, convenient, and reliable microvolume quantification of DNA, RNA, and protein samples. Its compact design, standalone operation, and trusted NanoDrop technology make it an essential tool for academic laboratories, teaching institutions, and research facilities requiring rapid nucleic acid and protein quality assessment.
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