Thermo Scientific™ HyperSep™ C18 Cartridges

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Particle Size: 40 to 60 μm

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Specifications:
Application Solid Phase Extraction
Storage Temperature Ambient
Product Type Solid Phase Extraction Cartridge
Product Brand Thermo Fisher Scientific™
Product Grade Analytical grade

Thermo Scientific™ HyperSep™ C18 Cartridges are high-performance solid phase extraction (SPE) devices designed for efficient sample preparation prior to chromatographic analysis. These cartridges contain a hydrophobic C18 bonded silica phase that provides strong retention of nonpolar to moderately polar compounds from aqueous matrices.

By selectively retaining organic analytes while removing interfering matrix components, HyperSep C18 cartridges improve analytical accuracy, method robustness, and instrument performance. They are widely used in biological, pharmaceutical, environmental, and forensic laboratories for sample cleanup and concentration prior to techniques such as HPLC, LC-MS, and GC analysis.

The cartridges are manufactured in industry-standard formats and can be processed using vacuum manifolds, positive pressure systems, or centrifugation, enabling flexible workflow integration in both routine and high-throughput laboratories.

Key Features

  • High-purity C18 bonded silica sorbent for reversed-phase SPE applications
  • Strong retention of nonpolar and moderately polar analytes
  • Efficient extraction of organic compounds from aqueous samples
  • Wide range of bed weights and cartridge volumes for method flexibility
  • Compatible with vacuum, positive pressure, and centrifugation processing
  • Reproducible and reliable sample preparation performance
  • Suitable for both routine analytical workflows and method development

Applications

  • Pharmaceutical and drug analysis
  • Environmental contaminant monitoring
  • Forensic toxicology sample preparation
  • Food and beverage analysis
  • Biological sample cleanup prior to LC-MS or HPLC
  • Extraction of pesticides, hydrocarbons, and organic pollutants

Available Models and Ordering Information

Catalog NumberBed WeightColumn CapacityPack Size
60108-37625 mg1 mL100
60108-39050 mg1 mL100
60108-302100 mg1 mL100
60108-765100 mg3 mL30
60108-303200 mg3 mL50
60108-304500 mg3 mL50
60108-3011000 mg6 mL30
60108-305500 mg6 mL30
60108-786500 mg10 mL50
60108-7761000 mg15 mL20
60108-7012000 mg15 mL20
60108-7802000 mg25 mL20
60108-7025000 mg25 mL20
60108-70310 g75 mL10

HyperSep™ SPE System

The HyperSep™ SPE platform includes both traditional cartridges and 96-well plate formats designed to support high-throughput workflows. The HyperSep-96™ system integrates SPE sorbents into a 96-well plate configuration, enabling rapid processing while maintaining analytical reproducibility.

The flexible plate design allows customization of sorbent chemistries across wells, supporting efficient method development and scaling without the need for revalidation.

Thermo Scientific™ HyperSep™ C18 Cartridges provide reliable and reproducible solid phase extraction for laboratories requiring high-quality sample preparation prior to chromatographic analysis. With a hydrophobic C18 phase optimized for retention of nonpolar compounds and a wide selection of cartridge formats, these SPE devices support a broad range of analytical workflows in pharmaceutical, environmental, forensic, and life science research laboratories.

  • Description:   1 g Bed Weight; 6 mL Column Volume, 30/pk 500 mg bed weight; 3 mL Column Volume, 50/Pk 100 mg Bed Weight; 1 mL Column Volume, 100/pk 200 mg Bed Weight; 3 mL Column Volume, 50/pk 500 mg Bed Weight; 6 mL Column Volume, 30/pk 50 mg bed weight, 1 mL column volume, 100/pk 2 g Bed Weight; 15 mL Column Volume, 20/pk 5 g Bed Weight; 25 mL Column Volume, 20/pk 10 g Bed Weight; 75 mL Column Volume, 10/pk 1 g bed weight; 15 mL column volume, 20/Pk 100 mg bed weight; 3 mL column volume, 50/Pk 2 g bed weight; 25 mL column volume, 20/Pk 25 mg bed weight; 1 mL column volume, 100/Pk 500 mg bed weight; 10 mL Column Volume, 50/Pk


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