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Thermo Scientific™ cis-Dichlorodiamineplatinum(II), 99.99% (Trace Metal Basis)
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Specifications:
| Application | molecular biology, Apoptosis | ||
| Storage Temperature | -20°C | ||
| Product Type | Biochemical Reagent | Forms | Solid |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Molecular Biology | Formula | Cl₂H₆N₂Pt |
Thermo Scientific™ cis-Dichlorodiamineplatinum(II) (commonly known as Cisplatin) is a high-purity platinum coordination compound widely used in oncology, coordination chemistry, and biochemical research.
This reagent-grade product (99.99% trace metal purity) is a benchmark platinum-based antineoplastic agent that forms DNA crosslinks, inhibiting DNA replication and transcription, ultimately inducing apoptosis in proliferating cells.
Cisplatin is essential in cancer research, drug development, and metallopharmaceutical studies, serving as a reference compound for platinum-based chemotherapeutics.
Key Features
- Ultra-High Purity: 99.99% (trace metal basis) with total trace metal impurities ≤0.01%.
- Platinum Content: 64.0–66.0% Pt assay.
- Mechanism of Action: DNA crosslinking agent that inhibits replication and induces cell death.
- Physical Appearance: Yellow to orange crystalline or powdered solid.
- Infrared Spectrum: Conforms to analytical reference standard.
- Research Grade: Ideal for chemical, biochemical, and pharmacological studies.
- Research Use Only (RUO): Not for therapeutic or diagnostic applications.
Chemical Identifiers
| Property | Value |
|---|---|
| IUPAC Name | Dichloroplatinumbis(ylium) diamine |
| Synonyms | Cisplatin, Cis-DDP, Platinol-AQ, Platidiam, CPDD, CACP, Cis-Pt(II) |
| CAS Number | 15663-27-1 |
| Molecular Formula | Cl₂H₆N₂Pt |
| Molecular Weight | 300.04 g/mol |
| InChI Key | BSJGASKRWFKGMV-UHFFFAOYSA-L |
| SMILES | N.N.Cl[Pt++]Cl |
| MDL Number | MFCD00011623 |
Specifications
| Parameter | Specification |
|---|---|
| Purity (Trace Metal Basis) | 99.99% |
| Platinum Content (Pt) | 64.0 – 66.0% |
| Total Trace Metal Impurities | ≤0.01% |
| Form | Powder or crystals |
| Color | Yellow to orange |
| Infrared Spectrum | Conforms |
| Storage Conditions | Cool, dry place; tightly closed |
| Packaging | Glass bottle |
| Intended Use | Research Use Only (RUO) |
Applications
- Cancer Research: Study of platinum-induced DNA crosslinking and apoptosis.
- Drug Development: Reference compound for cisplatin analogs and platinum-based chemotherapy drugs.
- Coordination Chemistry: Model for platinum(II) complex formation.
- Biochemical Research: Mechanistic studies on DNA–metal interactions.
- Crystallography: Structural studies of protein–platinum complexes.
- Medicinal Chemistry: Investigating cytotoxic mechanisms of metal-based drugs.
The Thermo Scientific™ cis-Dichlorodiamineplatinum(II), 99.99% (trace metal basis) is a high-purity platinum compound trusted for oncological, chemical, and biochemical research.
With precise metal purity and consistent composition, this compound is the standard reference reagent for studying the mechanism of platinum-based antitumor agents and DNA interactions.
- Pack Size: 250mg 1g 5g