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Thermo Scientific™ Cecropin A (1-7) -Melittin (2-9) Hybrid Peptide
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Sequence: Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-NH2
Specifications:
| Application | cell Signalling | ||
| Storage Temperature | -30°C to -10°C | ||
| Product Type | Proteins & Peptides | Forms | lyophilized powder |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Molecular Biology | Formula | [CA(1-7)M(2-9)NH₂] |
Thermo Scientific™ Cecropin A (1-7)-Melittin (2-9) Hybrid Peptide is a synthetic antimicrobial peptide fragment designed for cellular and molecular biology applications. Supplied as a high-purity HPLC-purified lyophilized powder, this hybrid peptide combines the N-terminal sequence of Cecropin A with the central helix of Melittin, resulting in potent membrane-disrupting activity.
The peptide is known to induce the release of carboxyfluorescein encapsulated in phosphatidylcholine liposomes, making it useful for studies of membrane permeability, liposome stability, and peptide-membrane interactions.
Key Features
- Hybrid peptide – combines Cecropin A (1–7) with Melittin (2–9).
- Defined sequence – Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-NH₂.
- High purity – HPLC-purified, lyophilized powder.
- Molecular weight – 1770.29 g/mol.
- Research-grade quality – for RUO (Research Use Only).
- Functional activity – causes dye release from carboxyfluorescein-loaded liposomes.
Applications
- Studies of membrane permeability and disruption.
- Liposome release assays.
- Antimicrobial peptide research.
- Cellular and molecular biology applications involving peptide-membrane interactions.
Technical Specifications
| Property | Value |
|---|---|
| Product Name | Cecropin A (1-7)-Melittin (2-9) Hybrid Peptide |
| Catalog Numbers | J66741.MCR (1 mg), J66741.EXD (0.5 mg) |
| Common Name | [CA(1-7)M(2-9)NH₂] |
| Sequence | Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-NH₂ |
| Molecular Weight | 1770.29 g/mol |
| Format | Lyophilized powder |
| Purification Method | HPLC |
| Storage Conditions | –30 °C to –10 °C |
| Regulatory Status | RUO – Research Use Only |
Available Formats
| Catalog Number | Quantity | Format |
|---|---|---|
| J66741.MCR | 1 mg | Lyophilized powder |
| J66741.EXD | 0.5 mg | Lyophilized powder |
Thermo Scientific™ Cecropin A (1-7)-Melittin (2-9) Hybrid Peptide is a high-purity, research-grade peptide designed for molecular and cellular studies involving membrane disruption. With a defined sequence, verified purity, and proven activity in liposome dye-release assays, it is a reliable tool for antimicrobial peptide research and membrane interaction studies.
- Pack Size: 1 mg 0.5 mg