MCE 6-Amino-6-deoxy-β-cyclodextrin (≥95.0%)

MedChemExpress (MCE) 6-Amino-6-deoxy-β-cyclodextrin (≥95.0%) is a functionalized cyclodextrin derivative widely used in analytical chemistry, pharmaceutical research, and materials science. This amino-modified β-cyclodextrin serves as a versatile intermediate for the synthesis of advanced cyclodextrin derivatives and as an effective chiral selector in separation sciences.

Its unique structure—combining the inclusion complex-forming ability of cyclodextrins with a reactive amino group—enables applications in capillary electrophoresis, drug delivery research, and catalyst development. The compound is particularly valuable in chiral discrimination and molecular recognition studies.

Key Features

• Functionalized Cyclodextrin Derivative
  Amino substitution enhances reactivity and enables further chemical modification.
• Chiral Selector Capability
  Effective for enantioselective separation of α-amino acid derivatives in capillary electrophoresis.
• High Purity (≥95%)
  Suitable for advanced research and analytical applications.
• Versatile Research Utility
  Can be used as a precursor for synthesizing modified cyclodextrins and functional materials.
• Inclusion Complex Formation
  Retains the host–guest chemistry properties characteristic of β-cyclodextrins.

Applications

Analytical Chemistry

• Chiral separation of amino acid derivatives
• Capillary electrophoresis (CE) applications
• Enantioselective analysis

Pharmaceutical & Drug Delivery Research

• Development of drug inclusion complexes
• Solubility enhancement studies
• Controlled drug release systems

Chemical Synthesis & Materials Science

• Intermediate for cyclodextrin derivative synthesis
• Functionalization of polymers and biomaterials
• Catalyst development (e.g., grafting onto chitosan matrices)

Biochemical Research

• Molecular recognition studies
• Host–guest interaction investigations
• Supramolecular chemistry research

Chemical Information

Solubility & Preparation

• Solvent: DMSO (up to 100 mg/mL with sonication)
• Stock Solution Preparation:
  Prepare appropriate concentrations (e.g., 1–50 mM) based on experimental needs
• Note: Use fresh, dry DMSO to ensure optimal solubility

Handling & Storage

• Storage Temperature: 4°C (under nitrogen, protected from moisture)
• Stock Solutions:
  • −80°C: Stable up to 6 months
  • −20°C: Stable up to 1 month
• Handling: Hygroscopic material; avoid repeated freeze–thaw cycles

Ordering Information

Unique Advantages

• Enhanced Functional Reactivity
  Amino group enables derivatization and conjugation in advanced applications.
• Excellent Chiral Recognition Properties
  Ideal for enantioselective separation in analytical chemistry.
• Broad Research Compatibility
  Applicable across chemistry, biochemistry, and pharmaceutical research fields.
• Supramolecular Versatility
  Maintains inclusion complex capability for host–guest interactions.

MCE 6-Amino-6-deoxy-β-cyclodextrin (≥95.0%) is a highly versatile cyclodextrin derivative designed for advanced research applications in analytical chemistry, drug delivery, and materials science. Its dual functionality—combining chiral recognition and chemical reactivity—makes it a valuable tool for laboratories engaged in cutting-edge molecular and separation studies.