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Thermo Scientific™ Ionomycin calcium salt ≥99%, 5mg
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Formula: C₄₁H₇₀CaO₉
Storage Temperature: Freezer
CAS Number: 56092-82-1
Specifications:
| Application | Cell culture, molecular biology, cell Signalling | ||
| Storage Temperature | -20°C | ||
| Product Type | Antibiotic | Forms | Solid |
| Product Brand | Thermo Fisher Scientific™, thermo Scientific | ||
| Product Grade | Analytical grade | Formula | C₄₁H₇₀CaO₉ |
Ionomycin Calcium Salt is a potent calcium ionophore commonly used in cell biology to increase intracellular calcium levels. This polyether antibiotic is widely utilized to stimulate calcium-dependent processes, such as T-cell activation, signal transduction, and induction of apoptosis. Ionomycin is structurally related to other calcium ionophores but is more effective than A23187 in many applications due to its higher Ca²⁺ selectivity.
This compound is supplied as a high-purity, research-grade reagent for use in signal transduction, immunology, neuroscience, and cell cycle research.
Applications
| Research Area | Use/Application |
|---|---|
| Cell Biology | Induction of intracellular Ca²⁺ elevation |
| Neuroscience | Triggers apoptotic degeneration in cortical neurons |
| Immunology | Stimulates calcium-dependent T-cell activation pathways |
| Cell Cycle Analysis | Induces cell cycle arrest at the G1 phase |
| Signal Transduction | Facilitates studies involving Ca²⁺-dependent signaling cascades |
Chemical Identifiers
| Property | Value |
|---|---|
| IUPAC Name | calcium (4R,6S,8S,12R,14R,16E,18R,19R,20S,21S)-... |
| InChI Key | RULWQOBWZOQCOY-SQNLDGQHSA-M |
| SMILES | [Ca++].CC@H... |
Specifications
| Property | Specification |
|---|---|
| Appearance | White powder or crystals |
| Purity (HPLC) | ≥98.5% |
| Form | Powder/crystalline powder |
Safety & Handling
- Hazards: Handle with care; for research use only (RUO)
- Recommended PPE: Gloves, lab coat, safety glasses
- Storage Conditions: Store at room temperature in a tightly closed container, away from light and moisture
Thermo Scientific™ Ionomycin Calcium Salt is a premium-quality reagent trusted for intracellular calcium modulation in various biological systems. It is ideal for applications requiring precise manipulation of Ca²⁺ signaling, such as immune cell stimulation and neurodegeneration studies.