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Gibco™ Primary Rat Cortex Neurons, Sprague Dawley
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Specifications:
| Application | Cell culture | ||
| Storage Temperature | Store Cells in Liquid Nitrogen untill ready to use | ||
| Product Type | cell Lines | Forms | Lyophilized |
| Product Brand | Thermo Fisher Scientific™, Gibco | ||
| Product Grade | Cell Culture | ||
Gibco™ Primary Rat Cortex Neurons (Sprague Dawley) are high-purity, cryopreserved neurons isolated from embryonic day-18 (E18) rat cortices. These cells offer a ready-to-use, flexible alternative to freshly isolated neurons, ensuring consistent performance and reducing the need for animal dissection.
Each vial contains neurons validated for post-thaw viability (≥50%), neuronal purity (>70%), and functional activity, including spontaneous synchronous calcium flux and synaptic release events. These neurons provide a reproducible platform for research in neuroscience, drug discovery, and neurotoxicity testing.
Key Features
- Ready-to-use, cryopreserved neurons: Convenient and consistent alternative to freshly isolated cortical neurons.
- High viability: ≥50% post-thaw viability with reproducible recovery.
- High purity: ≥70% neuronal phenotype confirmed via immunocytochemistry.
- Functionally validated: Demonstrated calcium signaling and synaptic release activity.
- Derived from Sprague Dawley rats: Embryonic day-18 (E18) cortices.
- Quality assured: Tested for sterility, mycoplasma, and viability.
- Research Use Only (RUO): Not for diagnostic or therapeutic use.
Specifications
| Parameter | Specification |
|---|---|
| Species | Rat (Rattus norvegicus, Sprague Dawley) |
| Tissue | Cortex |
| Age | Embryonic day 18 (E18) |
| Cell Type | Neural cells (neurons) |
| Form | Cryopreserved |
| Cell Quantity | 1 × 10⁶ (A36511) or 4 × 10⁶ (A36512) |
| Culture Type | Mammalian cell culture |
| Tested For | Purity, sterility, viability, mycoplasma |
| Storage Conditions | Vapor-phase liquid nitrogen |
| Intended Use | Research Use Only (RUO) |
Applications
- Neurobiology research: Study of neuronal development, differentiation, and connectivity.
- Drug discovery: Testing compounds affecting neuronal signaling and synaptic activity.
- Electrophysiology: Ideal for calcium imaging and patch-clamp recording studies.
- Neurotoxicity screening: Assessment of cytotoxic effects on neuronal populations.
- Neural network modeling: Investigations of in vitro network formation and function.
The Gibco™ Primary Rat Cortex Neurons (Sprague Dawley) provide a reliable, functionally validated neuron model for advanced in vitro neurobiology.
With consistent post-thaw viability, high neuronal purity, and validated synaptic activity, these neurons deliver reproducible results for functional assays, toxicity testing, and CNS research—all with the quality assurance of Gibco™ cGMP manufacturing.
- Pack Size: 1 x 10^6 cells 4 x 10^6