Apollo Sci. TCEP-HCL, 98%
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Used in the reduction of disulphide groups
Specifications:
| Application | molecular biology | ||
| Storage Temperature | 2-8°C | ||
| Product Type | Laboratory Chemical | Forms | Powder |
| Product Brand | Apollo Scientific | ||
| Product Grade | Analytical grade | Formula | C₉H₁₆ClO₆P |
Apollo Scientific TCEP-HCl is a high-purity, water-soluble reducing agent widely used in biochemistry and molecular biology for reducing disulfide bonds in proteins and peptides. Known for its superior stability compared to DTT, TCEP-HCl is a reliable choice for applications requiring efficient and consistent reduction under aqueous conditions.
Key Features:
- High Purity:
- 98% pure formulation ensures reliable and reproducible results.
- Stable and Effective:
- More stable than DTT, TCEP-HCl does not oxidize easily, making it ideal for air-exposed workflows.
- Water Soluble:
- Easily dissolves in water, simplifying preparation and application in aqueous systems.
- Efficient Reduction:
- Selectively reduces disulfide bonds in proteins and peptides.
Applications:
- Reduction of Disulfides:
- Ideal for reducing protein and peptide disulfide bonds in biochemical research.
- Sample Preparation:
- Used in mass spectrometry workflows to prepare reduced samples.
- Biochemical Analysis:
- Supports enzyme studies, protein assays, and other reduction-based applications.
Specifications:
| Attribute | Details |
|---|---|
| Chemical Formula | C₉H₁₆ClO₆P |
| Molecular Weight | 286.65 g/mol |
| Purity | 98% |
| Melting Point | 177–178 °C |
| Water Solubility | Fully soluble |
| Stability | More stable than DTT |
| Storage Temperature | Refrigerator (2–8°C) |
| MDL Number | MFCD00145469 |
| CAS Number | 51805-45-9 |
| Hazard Classification | UN 3261, ADR 8, II (Corrosive, Danger) |
Advantages:
| Feature | Benefit |
|---|---|
| High Stability | Remains active longer than DTT under ambient conditions. |
| Water Solubility | Simplifies handling and preparation. |
| High Purity | Reduces variability in experimental results. |
| Selective Reduction | Efficiently reduces protein disulfides without side reactions. |
Handling and Storage:
- Storage Conditions: Store in a refrigerator (2–8°C) for optimal stability.
- Safety Precautions: Classified as Corrosive; wear appropriate personal protective equipment (PPE) when handling.
- Shipping Classification: UN 3261, ADR 8, II (corrosive).
Chemical and Physical Properties:
| Property | Value |
|---|---|
| Synonyms | 3,3',3''-Phosphinetriyltripropanoic acid hydrochloride, TCEP |
| Molecular Structure | Tris(2-carboxyethyl)phosphine hydrochloride |
| Density | Not specified |
| Boiling Point | Not specified |
For efficient and reliable reduction of disulfides in proteins and peptides, Apollo Scientific TCEP-HCl is an excellent choice for your biochemical and molecular biology needs.
- Pack Size: 5g 10g 25g
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