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Proteintech™ TRIP13 Monoclonal Antibody (1F1E9), 150 µL
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Specifications:
| Application | Western Blot | ||
| Storage Temperature | -20°C | ||
| Product Type | Primary Antibodies | Forms | Liquid |
| Product Brand | Proteintech | ||
| Product Grade | Molecular Biology | ||
The Proteintech TRIP13 Monoclonal Antibody (Clone 1F1E9) is a high-specificity antibody designed for the detection of TRIP13 (Thyroid Hormone Receptor Interactor 13), a protein involved in transcriptional regulation and cell cycle processes. This antibody recognizes TRIP13 derived from a fusion protein immunogen and is validated for Western blot applications, providing reliable detection in human, mouse, and rat samples.
TRIP13 plays a role in regulating transcription through interaction with thyroid hormone receptors (TRs) and is implicated in cellular processes such as chromosome segregation, mitotic checkpoint regulation, and tumor biology. Its involvement in interactions with viral proteins such as HPV16 E1 further highlights its significance in cancer and molecular biology research.
Key Features
- Specific for TRIP13 transcription-associated protein
- Monoclonal antibody clone 1F1E9
- Reactivity: Human, Mouse, Rat
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Validated for:
- Western Blot (WB): 1:5,000
- Supplied as unconjugated liquid antibody
- High concentration: 1000 µg/mL
- Purified using Protein G
- Stable formulation in PBS with 50% glycerol
- Preserved with 0.02% sodium azide
Applications
This antibody is ideal for:
- Western blot detection of TRIP13 protein expression
- Studies of transcriptional regulation mechanisms
- Research on thyroid hormone receptor signaling pathways
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Investigation of:
- Mitotic checkpoint regulation
- Chromosome segregation
- Cancer biology and tumor progression
- Virus-host interactions (e.g., HPV-related studies)
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | Proteintech TRIP13 Monoclonal Antibody (1F1E9) |
| Catalog Number | 67759-1-Ig |
| Type | Antibody |
| Class | Monoclonal |
| Clone | 1F1E9 |
| Host / Isotype | Mouse / IgG1 |
| Species Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1000 µg/mL |
| Amount | 150 µg |
| Volume | 150 µL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Preservative | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Immunogen Information
| Parameter | Details |
|---|---|
| Immunogen | TRIP13 Fusion Protein Ag6595 |
Target Information
TRIP13 (Thyroid Hormone Receptor Interactor 13) is a transcription-associated protein that interacts with the ligand-binding domain of thyroid hormone receptors (TRs). Unlike many TR-interacting proteins, TRIP13 can bind independently of thyroid hormone presence.
TRIP13 is involved in cell cycle regulation, particularly in processes such as chromosome alignment and mitotic checkpoint control. It has also been associated with tumor biology, with emerging evidence suggesting roles in cancer progression and genomic stability. Additionally, its interaction with HPV16 E1 protein indicates a potential link to viral oncogenesis.
Advantages
- High specificity for TRIP13 protein detection
- Optimized for reliable Western blot performance
- Broad species reactivity for versatile use
- Ideal for cell cycle, transcription, and cancer research
- Consistent monoclonal antibody performance
The Proteintech TRIP13 Monoclonal Antibody (1F1E9) is a dependable tool for researchers investigating transcriptional regulation, cell cycle control, and tumor biology. Its validated Western blot performance and strong specificity make it well-suited for molecular biology and oncology research applications.