Thermo Scientific™ NanoDrop™ Ultra

The Thermo Scientific™ NanoDrop™ Ultra Series represents the next generation of microvolume UV-Vis spectrophotometers and fluorometers, delivering exceptional accuracy, sensitivity, and workflow efficiency for DNA, RNA, and protein analysis. Designed for modern laboratories, these instruments enable rapid quantification and qualification using sample volumes as low as 1–2 μL, eliminating the need for cuvettes and reducing sample waste.

With integrated Acclaro™ Sample Intelligence technology, the NanoDrop Ultra provides advanced contaminant detection, real-time sample integrity insights, and enhanced measurement accuracy. Combined with a high-resolution touchscreen interface, powerful connectivity options, and optional compliance software, this system supports reliable, high-throughput workflows across genomics, proteomics, molecular biology, biotechnology, and pharmaceutical research.

Key Features

• Microvolume measurement with as little as 1 μL sample volume
• Integrated Acclaro™ Sample Intelligence technology for contaminant detection and correction
• UV-Vis spectrophotometry and optional fluorometry in a single platform
• Full-spectrum analysis (190–850 nm) for comprehensive sample characterization
• High accuracy and reproducibility with auto-ranging pathlength (0.03–1.0 mm)
• Fast measurement times: ≤7 seconds (standard)
• Large 10.1-inch high-definition touchscreen interface
• Advanced connectivity: Wi-Fi, Ethernet, USB, Bluetooth™
• Direct LIMS integration via RESTful API
• Compatible with cloud storage platforms (OneDrive, Google Drive, Thermo Fisher Connect)
• Optional 21 CFR Part 11 compliance tools with SciVault™ 2 software

Applications

• DNA and RNA quantification (A260, purity ratios A260/A280, A260/A230)
• Protein quantification (A280, A205, BCA, Bradford, Lowry assays)
• Oligonucleotide and labeled nucleic acid analysis
• Microbial culture density measurement (OD600)
• UV-Vis spectral analysis and custom methods
• Fluorescence-based quantification (select models)
• Quality control for PCR, qPCR, sequencing, and downstream molecular workflows

Available Models

Acclaro™ Sample Intelligence Technology

• Contaminant Detection & Correction
  Automatically identifies and compensates for contaminants to improve measurement accuracy
• Sample Integrity Monitoring
  Detects bubbles and anomalies that may compromise results
• Enhanced Data Confidence
  Combines sensor data and image analysis to ensure reliable quantification

Workflow Optimization Features

• Auto-Measure & Auto-Blank for rapid, repeatable measurements
• Integrated qPCR recipe calculator for accurate reaction preparation
• Customizable data export and reporting
• Triplicate measurement capability for improved precision
• Optional Acclaro Pro Software for enhanced accuracy in high-concentration samples

Connectivity & Data Management

• Direct export to cloud platforms (OneDrive, Google Drive, Thermo Fisher Connect)
• LIMS integration via RESTful API
• Multiple connectivity options: USB, Ethernet, Wi-Fi, Bluetooth™
• Direct printing from instrument or PC
• Flexible data formats: Excel™, PDF, image files

Compliance & Data Integrity

• Optional SciVault 2 for 21 CFR Part 11 compliance
• Supports user account management, audit trails, and digital signatures
• Centralized or on-instrument data control options

Technical Specifications

The Thermo Scientific™ NanoDrop™ Ultra Series delivers a powerful combination of precision, speed, and intelligent data analysis for modern life science laboratories. By integrating microvolume measurement, advanced contaminant detection, and seamless digital connectivity, it eliminates common workflow bottlenecks while improving data quality and confidence.

Whether for routine nucleic acid quantification or advanced protein analysis, the NanoDrop Ultra provides a compact, high-performance solution that enhances productivity and supports reliable results across a wide range of molecular biology and research applications.