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VWR® Deuterium oxide (D₂O 99.90% D) for NMR spectroscopy
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Specifications:
| Application | Analytical Chemistry, NMR spectroscopy | ||
| Storage Temperature | Ambient | ||
| Product Type | Laboratory Chemical | Forms | Liquid |
| Product Brand | VWR | ||
| Product Grade | Analytical grade | Formula | D₂O |
VWR® Deuterium Oxide (D₂O), commonly known as heavy water, is a high-purity deuterated solvent specifically designed for NMR spectroscopy of aqueous and polar samples.
With an isotopic enrichment of ≥99.90% deuterium (D), this solvent provides an excellent field-frequency lock signal and significantly reduces proton interference, making it essential for biochemical, pharmaceutical, and life science NMR applications.
Key Features & Benefits
1. Ultra-High Isotopic Enrichment
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≥99.90% D ensures:
- Minimal proton background signal
- Stable NMR lock performance
2. Ideal for Aqueous & Biological Samples
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Perfect for:
- Proteins, peptides, and biomolecules
- Water-soluble compounds
- Biological and metabolomics studies
3. High Purity & NMR Compliance
- Meets ¹H NMR reference conformity standards
- Ensures accurate and reproducible spectra
4. Versatile NMR Applications
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Suitable for:
- ¹H NMR (with solvent suppression techniques)
- ¹³C NMR
- 2D NMR (COSY, HSQC, NOESY, etc.)
5. Stable & Easy Handling
- Supplied in glass bottles
- Stable under ambient storage conditions
Applications
- NMR analysis of aqueous samples
- Protein and peptide structure studies
- Metabolomics and biochemical research
- Pharmaceutical formulation studies
- Exchangeable proton studies (OH, NH groups)
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | Deuterium Oxide (Heavy Water) |
| Chemical Formula | D₂O |
| CAS Number | 7789-20-0 |
| Molecular Weight | 20 g/mol |
| Isotopic Enrichment | ≥99.90% D |
| Boiling Point | 101.3 °C |
| Melting Point | 3.8 °C |
| Density | 1.1 g/cm³ (20 °C) |
| Technique | NMR Spectroscopy |
| Storage | Ambient |
Ordering Information
| Product Code | Pack Size | Packaging |
|---|---|---|
| 84541.0011 | 10 mL | Glass bottle |
| 84541.0025 | 25 mL | Glass bottle |
| 84541.0100 | 100 mL | Glass bottle |
| 84541.0500 | 500 mL | Glass bottle |
Analytical Significance
Deuterium oxide plays a critical role in NMR by:
- Providing a deuterium lock signal for spectrometer stability
- Allowing analysis of water-soluble compounds
- Enabling study of exchangeable protons (–OH, –NH) through proton exchange
It is indispensable for:
- Biomolecular NMR studies
- Aqueous solution analysis
- Quantitative NMR (qNMR)
Unique Advantages
- Highest suitability for aqueous NMR applications
- Ultra-high isotopic purity ensures accurate results
- Compatible with biological and pharmaceutical samples
- Essential for modern metabolomics and proteomics workflows
- Reliable quality from Avantor
VWR® Deuterium Oxide (99.90% D) is a fundamental NMR solvent for aqueous systems, delivering high isotopic purity, stability, and analytical reliability. It is the preferred choice for laboratories conducting biochemical, pharmaceutical, and life science NMR studies.
- Pack Size: 10 mL Glass bottle 25 mL Glass bottle 100 mL Glass bottle 500 mL Glass bottle