Thermo Scientific™ Paraformaldehyde ≥97%

High-Purity Cross-Linking Fixative for Cell & Tissue Preservation

Thermo Scientific™ Paraformaldehyde (PFA) is a high-purity cross-linking fixative used for cell and tissue fixation in fluorescence microscopy, histology, and immunohistochemistry (IHC) applications. It polymerizes to formaldehyde upon heating and alkaline treatment (with sodium hydroxide), making it an ideal reagent for preparing formalin-based fixatives.

This ≥97% pure paraformaldehyde provides reliable fixation, preserving cellular and tissue structures while maintaining fluorescence integrity for downstream imaging and staining applications.

Key Features & Benefits

✅ High-Purity (≥97%) – Ensures consistent and effective fixation

✅ Cross-Linking Fixative – Preserves morphological and structural integrity of samples

✅ Fluorescence-Compatible – Ideal for fluorescence microscopy studies

✅ Customizable Fixative Preparation – Converts to formaldehyde with heating and NaOH addition

✅ Versatile Application – Suitable for cell fixation, tissue sectioning, and staining protocols

Applications

🔬 Fluorescence Microscopy – Fixative for fluorescent proteins and staining procedures

🦠 Histology & Immunohistochemistry (IHC) – Preserves cellular morphology for staining

🧬 Tissue & Cell Fixation – Used in formalin-based fixative preparation

🛠️ Electron Microscopy Sample Preparation – Ensures structural preservation for ultrastructural studies

Product Specifications

Usage Guidelines

• Preparation of Formaldehyde Solution
  • Dissolve paraformaldehyde powder in phosphate-buffered saline (PBS) or water
  • Heat to 60°C while stirring
  • Add a small amount of sodium hydroxide (NaOH) to adjust pH
  • Once dissolved, filter sterilize if required
• Fixation Procedure:
  • Use at 4% paraformaldehyde solution in PBS for standard fixation
  • Fix cells/tissues at room temperature or 4°C, depending on application

Regulatory & Safety Information

⚠️ For Research Use Only. Not intended for diagnostic, therapeutic, or human/animal use.

• Use in a well-ventilated area with appropriate personal protective equipment (PPE)
• Refer to the Safety Data Sheet (SDS) for proper handling and disposal guidelines

Why Choose Thermo Scientific™ Paraformaldehyde?

🔹 High-Purity (≥97%) – Reliable and reproducible fixation results

🔹 Optimized for Fluorescence Studies – Prevents autofluorescence interference

🔹 Customizable Fixative Preparation – Ensures flexibility in different applications

🔹 Trusted Quality & Performance – Manufactured under strict quality control

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