Thermo Scientific™ Ciprofloxacin 98%

Thermo Scientific Ciprofloxacin is a high-purity antibacterial compound belonging to the fluoroquinolone class, with a minimum purity of 98%. It is commonly used in research applications focused on bacterial infections, antibiotic resistance mechanisms, and pharmacological studies. Its broad-spectrum antibacterial activity makes it effective against a variety of gram-positive and gram-negative bacterial strains.

Chemical and Physical Properties:

• Synonyms:
  • 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
• Chemical Formula: C₁₇H₁₈FN₃O₃
• Molecular Weight: 331.35 g/mol
• CAS Number: 85721-33-1
• MDL Number: MFCD00185755

Specifications:

Applications:

1. Microbiological Research:

• Antimicrobial Studies:
  • Used to evaluate antibacterial activity against gram-positive and gram-negative bacteria, including E. coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
• Resistance Mechanism Research:
  • Studying the development of bacterial resistance, particularly in fluoroquinolone-resistant strains.

2. Pharmaceutical Research:

• Drug Development Studies:
  • Evaluating ciprofloxacin’s pharmacokinetics, efficacy, and combination therapies with other antibiotics.
• Formulation Studies:
  • Used in preclinical formulations for evaluating solubility, stability, and dissolution properties.

3. Molecular and Biochemical Research:

• Targeting DNA Gyrase and Topoisomerase IV:
  • As a fluoroquinolone, ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which are essential for DNA replication and transcription.
• Cytotoxicity Testing:
  • Used to assess the cytotoxic effects on bacterial cells versus eukaryotic cells.

Key Features:

1. High Purity:
   • Minimum purity of 98% ensures reliability and reproducibility in research applications.
2. Broad Spectrum Activity:
   • Active against a wide range of gram-positive and gram-negative bacteria.
3. Validated Specifications:
   • Strictly tested for loss on drying, sulfated ash, and purity using HPLC to ensure consistent quality.
4. Versatile Use:
   • Suitable for microbiological, pharmaceutical, and molecular biology research.

Packaging Information:

Storage and Handling:

• Storage Temperature: Store in a freezer (-20°C) to maintain stability and potency.
• Handling Precautions:
  • Use personal protective equipment (PPE) such as gloves and safety goggles.
  • Avoid inhalation or direct skin contact during handling.

Thermo Scientific Ciprofloxacin 98% is a reliable choice for researchers studying bacterial infections, antibiotic resistance, and fluoroquinolone pharmacodynamics. Its broad-spectrum activity, high purity, and stringent quality control make it suitable for diverse microbiological and pharmaceutical applications.