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Fmoc-Lys(Fmoc)-OH, also known as Nα,Nε-Di-Fmoc-L-lysine, is a high-purity, dual-protected lysine derivative used in Fmoc-based solid-phase peptide synthesis (SPPS). It features Fmoc protection on both the α-amino group and the ε-amino side chain, enabling controlled peptide assembly and making it particularly useful for branched peptide synthesis.
This reagent is widely used in custom peptide synthesis, pharmaceutical research, peptide vaccine development, multivalent peptide design, drug delivery research, protein engineering, and bioorganic chemistry. The dual Fmoc protection strategy allows lysine to serve as a branching point for dendritic, multivalent, or polymeric peptide structures.
Key Features
| Feature | Details |
|---|---|
| High Purity | ≥97.5% by HPLC for reliable peptide synthesis |
| Dual Fmoc Protection | Protects both the α-amino and ε-amino groups of lysine |
| Branched Peptide Synthesis | Enables preparation of dendritic and multivalent peptide structures |
| SPPS Compatible | Suitable for Fmoc-based solid-phase peptide synthesis workflows |
| High Enantiomeric Purity | ≥99.0% for consistent stereochemical performance |
| Versatile Research Use | Suitable for peptide vaccines, peptide therapeutics, protein engineering, and bioorganic chemistry |
Chemical Properties & Identifiers
| Property | Value |
|---|---|
| Product Name | Fmoc-Lys(Fmoc)-OH, ≥97.5% HPLC |
| Synonym | Nα,Nε-Di-Fmoc-L-lysine |
| CAS Number | 78081-87-5 |
| Empirical Formula | C₃₆H₃₄N₂O₆ |
| Molecular Weight | 590.66 g/mol |
| MDL Number | MFCD00080275 |
| UNSPSC Code | 12352209 |
| Form | Powder |
| Melting Point | 170–180 °C |
| Assay | ≥97.5% by HPLC |
| Enantiomeric Purity | ≥99.0% |
| Water Content | ≤2.0% by Karl Fischer titration |
| Storage Temperature | 2–30 °C |
| Functional Groups | Fmoc, amine, carboxylic acid |
Applications
Fmoc-Lys(Fmoc)-OH is suitable for:
- Fmoc-based solid-phase peptide synthesis
- Incorporation of lysine residues into synthetic peptides
- Branched peptide synthesis
- Dendritic and multivalent peptide design
- Peptide vaccine and antigenic epitope presentation research
- Peptide-based pharmaceutical and drug discovery research
- Protein engineering and structural biology studies
- Peptide modification and functionalized peptide synthesis
- Polymeric peptide conjugates and drug delivery research
- Bioorganic chemistry and peptidomimetic synthesis
Ordering Information
| Catalog Number | Quantity |
|---|---|
| 8520410005 | 5 g |
| 8520410025 | 25 g |
| 8520410100 | 100 g |
Storage & Handling
Store at 2–30 °C in a dry, tightly sealed container. Protect from moisture, oxidation, and extreme temperatures. Handle in a suitable laboratory environment using appropriate personal protective equipment, including gloves, lab coat, and safety goggles.
Research Use Statement
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Specification: Fmoc-Lys(Fmoc)-OH
Fmoc-Lys(Fmoc)-OH, also known as Nα,Nε-Di-Fmoc-L-lysine, is a high-purity, dual-protected lysine derivative used in Fmoc-based solid-phase peptide synthesis (SPPS). It features Fmoc protection on both the α-amino group and the ε-amino side chain, enabling controlled peptide assembly and making it particularly useful for branched peptide synthesis.
This reagent is widely used in custom peptide synthesis, pharmaceutical research, peptide vaccine development, multivalent peptide design, drug delivery research, protein engineering, and bioorganic chemistry. The dual Fmoc protection strategy allows lysine to serve as a branching point for dendritic, multivalent, or polymeric peptide structures.
Key Features
| Feature | Details |
|---|---|
| High Purity | ≥97.5% by HPLC for reliable peptide synthesis |
| Dual Fmoc Protection | Protects both the α-amino and ε-amino groups of lysine |
| Branched Peptide Synthesis | Enables preparation of dendritic and multivalent peptide structures |
| SPPS Compatible | Suitable for Fmoc-based solid-phase peptide synthesis workflows |
| High Enantiomeric Purity | ≥99.0% for consistent stereochemical performance |
| Versatile Research Use | Suitable for peptide vaccines, peptide therapeutics, protein engineering, and bioorganic chemistry |
Chemical Properties & Identifiers
| Property | Value |
|---|---|
| Product Name | Fmoc-Lys(Fmoc)-OH, ≥97.5% HPLC |
| Synonym | Nα,Nε-Di-Fmoc-L-lysine |
| CAS Number | 78081-87-5 |
| Empirical Formula | C₃₆H₃₄N₂O₆ |
| Molecular Weight | 590.66 g/mol |
| MDL Number | MFCD00080275 |
| UNSPSC Code | 12352209 |
| Form | Powder |
| Melting Point | 170–180 °C |
| Assay | ≥97.5% by HPLC |
| Enantiomeric Purity | ≥99.0% |
| Water Content | ≤2.0% by Karl Fischer titration |
| Storage Temperature | 2–30 °C |
| Functional Groups | Fmoc, amine, carboxylic acid |
Applications
Fmoc-Lys(Fmoc)-OH is suitable for:
- Fmoc-based solid-phase peptide synthesis
- Incorporation of lysine residues into synthetic peptides
- Branched peptide synthesis
- Dendritic and multivalent peptide design
- Peptide vaccine and antigenic epitope presentation research
- Peptide-based pharmaceutical and drug discovery research
- Protein engineering and structural biology studies
- Peptide modification and functionalized peptide synthesis
- Polymeric peptide conjugates and drug delivery research
- Bioorganic chemistry and peptidomimetic synthesis
Ordering Information
| Catalog Number | Quantity |
|---|---|
| 8520410005 | 5 g |
| 8520410025 | 25 g |
| 8520410100 | 100 g |
Storage & Handling
Store at 2–30 °C in a dry, tightly sealed container. Protect from moisture, oxidation, and extreme temperatures. Handle in a suitable laboratory environment using appropriate personal protective equipment, including gloves, lab coat, and safety goggles.
Research Use Statement
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Specification: Fmoc-Lys(Fmoc)-OH
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Specifiche
| Pack Size | 100g, 5g, 25g |