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Methanol, HiPerSolv CHROMANORM®, Ultra Plus for LC-MS, suitable for UPLC/UHPLC-MS instruments
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Specifications:
| Application | HPLC, Mass Spectrometry | ||
| Storage Temperature | Ambient | ||
| Product Type | Laboratory Chemical | Forms | Liquid |
| Product Brand | VWR | ||
| Product Grade | Analytical grade | Formula | CH₃OH |
The HiPerSolv CHROMANORM® Ultra Plus Methanol is a high-purity solvent specifically designed and quality-controlled for UPLC/UHPLC-MS applications. Manufactured and packaged under inert gas and filtered through a 0.1 µm filter, it meets the strictest requirements for LC-MS workflows, delivering exceptional baseline stability, low background, and minimal impurities.
This methanol ensures excellent signal reproducibility in gradient elution and MS detection, making it ideal for demanding analytical applications such as proteomics, metabolomics, pharmaceutical development, environmental testing, and clinical research.
Key Features
- Purity: ≥ 99.98% (GC, anhydrous basis)
- Exceptional Low Residues: ≤ 0.0001% w/w after evaporation
- Ultra-low Water Content: ≤ 0.03% w/w (Karl Fischer)
- Optical Quality: Minimal UV absorbance and drift in gradient elution
- Trace Metal Control: Each below strict ppb thresholds (Ag ≤ 50 ppb, Fe ≤ 20 ppb, Pb ≤ 20 ppb, etc.)
- Packaging: Glass bottles under inert gas for maximum stability
- Applications: Optimized for UHPLC, UPLC, LC-MS, and ESI+ detection workflows
Specifications (Selected Highlights)
| Property | Value |
|---|---|
| Appearance | Clear, colorless liquid |
| Density (20 °C) | 0.7918 g/cm³ |
| Boiling Point | 64.6 °C |
| Melting Point | –98 °C |
| Flash Point | 11 °C (closed cup) |
| UV Transparency | T210 nm ≥ 40%, T220 nm ≥ 65%, T230 nm ≥ 80%, T260 nm ≥ 98% |
| Gradient Elution Drift (220 nm) | ≤ 0.05 AU |
| Heavy Metals | ≤ 20–50 ppb (depending on element) |
| Fluorescence (Quinine 254/365 nm) | ≤ 0.5 ppb / ≤ 0.3 ppb |
| Storage Temperature | Ambient |
| Safety Classification | Flammable, Toxic (ADR: 3 (6.1), II; UN 1230) |
Applications
- Liquid Chromatography–Mass Spectrometry (LC-MS)
- Ultra-High-Performance Liquid Chromatography (UHPLC)
- Electrospray Ionization (ESI) MS
- Proteomics and Metabolomics Research
- Pharmaceutical Analysis & Quality Control
- Environmental and Clinical Testing
The Methanol, HiPerSolv CHROMANORM® Ultra Plus for LC-MS offers outstanding purity, ultra-low background noise, and rigorous trace metal control, ensuring maximum sensitivity and reproducibility in advanced LC-MS and UHPLC workflows. With its strict quality specifications, inert gas packaging, and broad application compatibility, it is the solvent of choice for high-performance analytical laboratories requiring the highest level of reliability in mass spectrometry.
- Pack Size: Glass bottle, 1L Glass bottle, 2.5L