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The Pierce™ Protein A/G Magnetic Beads are designed for efficient, high-yield immunoprecipitation (IP), co-immunoprecipitation (Co-IP), and antibody purification protocols. Coated with a recombinant fusion of Protein A and Protein G, these 1 μm magnetic beads provide a wide IgG-binding spectrum, enabling robust capture of antibodies from multiple species and isotypes. Their compatibility with manual and automated workflows makes them ideal for high-throughput screening and reproducible small-scale experiments.
Key Features and Benefits
- High Binding Capacity – Offers nearly 4x more antibody-binding capacity than conventional magnetic beads
- Wide IgG Specificity – Combines Fc-binding domains from both Protein A and Protein G for broader species/isotype coverage
- Low Background – Pre-blocked surface minimizes non-specific binding for cleaner eluates
- Crosslinking-Compatible – Enables antibody immobilization to prevent IgG contamination in IP eluates
- Automation-Ready – Compatible with Thermo Scientific™ KingFisher™ Instruments and other robotic systems
- Efficient Magnetic Handling – Ensures fast separation, minimal bead loss, and reproducible performance
Applications
- Immunoprecipitation (IP) and co-immunoprecipitation (Co-IP)
- Antibody purification
- Protein complex isolation for downstream analysis (e.g., SDS-PAGE, western blot)
- Pre-clearing of lysates
- High-throughput magnetic bead workflows
Technical Specifications
| Attribute | Details |
|---|---|
| Ligand | Recombinant Protein A/G |
| Particle Size | 1 μm |
| Binding Capacity | High (approx. 10 mg IgG/mL slurry) |
| Slurry Concentration | 10 mg/mL, 1% solids |
| Form | Liquid, magnetic bead suspension |
| Target | IgG (antibodies) |
| Species Compatibility | Mouse, Rabbit, Goat, Rat, Human, more |
| Bead Type | Magnetic affinity bead |
| Automation Compatible | Yes (e.g., KingFisher™ platforms) |
| Catalog Numbers | 88802 (1 mL), 88803 (5 mL) |
| Storage | 4°C (do not freeze) |
Kit Contents
- Protein A/G Magnetic Beads in liquid suspension
- Ready to use—no rehydration or activation required
Related Products
- Pierce™ Protein A Magnetic Beads
- Pierce™ Protein G Magnetic Beads
- Thermo Scientific™ KingFisher Flex Instrument
- Crosslinking reagents for covalent antibody coupling
The Pierce™ Protein A/G Magnetic Beads are a powerful, high-capacity tool for efficient antibody purification and immunoprecipitation. Whether you're performing IP manually or in an automated platform, these magnetic particles deliver clean, consistent, and scalable results, making them a dependable choice for research labs in immunology, proteomics, and molecular biology.
User Guide: Pierce Protein A/G Magnetic Beads
The Pierce™ Protein A/G Magnetic Beads are designed for efficient, high-yield immunoprecipitation (IP), co-immunoprecipitation (Co-IP), and antibody purification protocols. Coated with a recombinant fusion of Protein A and Protein G, these 1 μm magnetic beads provide a wide IgG-binding spectrum, enabling robust capture of antibodies from multiple species and isotypes. Their compatibility with manual and automated workflows makes them ideal for high-throughput screening and reproducible small-scale experiments.
Key Features and Benefits
- High Binding Capacity – Offers nearly 4x more antibody-binding capacity than conventional magnetic beads
- Wide IgG Specificity – Combines Fc-binding domains from both Protein A and Protein G for broader species/isotype coverage
- Low Background – Pre-blocked surface minimizes non-specific binding for cleaner eluates
- Crosslinking-Compatible – Enables antibody immobilization to prevent IgG contamination in IP eluates
- Automation-Ready – Compatible with Thermo Scientific™ KingFisher™ Instruments and other robotic systems
- Efficient Magnetic Handling – Ensures fast separation, minimal bead loss, and reproducible performance
Applications
- Immunoprecipitation (IP) and co-immunoprecipitation (Co-IP)
- Antibody purification
- Protein complex isolation for downstream analysis (e.g., SDS-PAGE, western blot)
- Pre-clearing of lysates
- High-throughput magnetic bead workflows
Technical Specifications
| Attribute | Details |
|---|---|
| Ligand | Recombinant Protein A/G |
| Particle Size | 1 μm |
| Binding Capacity | High (approx. 10 mg IgG/mL slurry) |
| Slurry Concentration | 10 mg/mL, 1% solids |
| Form | Liquid, magnetic bead suspension |
| Target | IgG (antibodies) |
| Species Compatibility | Mouse, Rabbit, Goat, Rat, Human, more |
| Bead Type | Magnetic affinity bead |
| Automation Compatible | Yes (e.g., KingFisher™ platforms) |
| Catalog Numbers | 88802 (1 mL), 88803 (5 mL) |
| Storage | 4°C (do not freeze) |
Kit Contents
- Protein A/G Magnetic Beads in liquid suspension
- Ready to use—no rehydration or activation required
Related Products
- Pierce™ Protein A Magnetic Beads
- Pierce™ Protein G Magnetic Beads
- Thermo Scientific™ KingFisher Flex Instrument
- Crosslinking reagents for covalent antibody coupling
The Pierce™ Protein A/G Magnetic Beads are a powerful, high-capacity tool for efficient antibody purification and immunoprecipitation. Whether you're performing IP manually or in an automated platform, these magnetic particles deliver clean, consistent, and scalable results, making them a dependable choice for research labs in immunology, proteomics, and molecular biology.
User Guide: Pierce Protein A/G Magnetic Beads
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Spécifications
| Pack Size | 1 mL, 5 mL |