Thermo Scientific™ Semicarbazide hydrochloride ≥99%

Semicarbazide hydrochloride is a white crystalline compound with high water solubility and ≥99% purity. It is widely used in organic synthesis, enzyme inhibition assays, and carbonyl compound derivatization. This reagent acts as a urease substrate, a monoamine oxidase (MAO) inhibitor, and a derivatizing agent for carbonyl functional groups, forming crystalline semicarbazones with well-defined melting points. Additionally, it plays a key role in heterocyclic compound synthesis and adsorption-based separation techniques.

Key Features & Benefits

• High Purity (≥99%): Suitable for sensitive analytical and preparative chemistry applications
• Water Soluble: Easily dissolves (>100 g/L) in aqueous systems for convenient use
• Versatile Functionality: Acts as a reagent, inhibitor, and intermediate in various chemical workflows
• Derivatization Agent: Converts carbonyl compounds into semicarbazones for identification and separation
• Applications in Neuroscience and Oncology: Cited in research on neural stem cells and tumor immunology
• Available in Multiple Quantities: Supplied in 100 g, 500 g, and 2500 g glass bottles

Chemical & Physical Properties

Applications

• Biochemical Research:
  • Urease substrate in enzymatic assays
  • MAO inhibitor in neuropharmacological studies
• Organic Synthesis:
  • Forms semicarbazones for the identification and separation of aldehydes and ketones
  • Intermediate in heterocyclic compound synthesis
• Analytical Chemistry:
  • Applied in derivatization protocols to aid in compound characterization
  • Used for adsorption-based separation on silica gel
• Pharmacological Studies:
  • Investigated in cancer and inflammation models (e.g., VAP-1 inhibition)
  • Used in memory and neurodegeneration models

Ordering Information

Storage & Handling

• Storage: Store in a tightly sealed container in a cool, dry place away from oxidizing agents
• Safety: Use appropriate PPE; for Research Use Only (RUO)

Thermo Scientific™ Semicarbazide Hydrochloride, 99% is a reliable and multifunctional reagent for use in derivatization, enzyme inhibition, synthetic chemistry, and biological assay development. With high purity, broad solubility, and a wide range of scientific applications, it is a staple chemical in both academic and industrial research environments.