Agilent 4200 TapeStation System

High-Throughput Automated Electrophoresis for Nucleic Acid Quality Control

The Agilent 4200 TapeStation system is a robust, fully automated high-throughput platform for fast and reliable DNA and RNA sample quality control. Designed to support critical workflows such as next-generation sequencing (NGS), biobanking, and vaccine development, the 4200 TapeStation enables true walk-away operation with minimal hands-on time, delivering consistent results for up to 96 samples per run.

Building on proven ScreenTape™ technology, the 4200 TapeStation ensures high reproducibility, low sample consumption, and full compatibility with Agilent’s complete range of DNA and RNA ScreenTape assays.

Key Features

• High Sample Throughput: Automates quality control of up to 96 DNA or RNA samples per run, maintaining a constant cost-per-sample regardless of throughput.
• Speed & Efficiency: Delivers results in 1–2 minutes per sample or under 90 minutes for 96 samples.
• Minimal Sample Input: Requires only 1–2 µL of DNA or RNA—even for high-sensitivity assays.
• Complete Assay Compatibility: Supports all Agilent DNA and RNA ScreenTape assays, including for genomic DNA, cell-free DNA, and RNA integrity.
• Flexible Sample Switching: Easily switch between DNA and RNA assays without reconfiguration.
• No Cross-Contamination: Each ScreenTape lane is individual and disposable.
• Reproducible Metrics: Includes RINe (RNA Integrity Number equivalent), DIN (DNA Integrity Number), and %cfDNA for reliable nucleic acid QC.
• Sustainable Operation: ACT label certified by My Green Lab for low environmental impact and energy-efficient performance.
• User-Friendly Workflow: Automated, walk-away operation with intuitive software and optional self-maintenance features.
• Seamless Compatibility: Optimized for NGS, biobank, and vaccine research pipelines.

Technical Specifications

How It Works

The 4200 TapeStation automates nucleic acid electrophoresis using Agilent’s ready-to-use ScreenTape technology. Each ScreenTape consumable contains 16 prefilled lanes that can be used independently and reused later if needed. After sample loading, the system performs automated size, concentration, and integrity analysis, freeing users for other tasks.

Applications

• NGS Sample QC: Rapid, reliable QC of RNA and DNA libraries during sequencing preparation using trusted quality metrics (RINe, DIN, %cfDNA).
• Biobank Sample Integrity: Accurate assessment of archived or incoming biospecimens with minimal sample consumption.
• Vaccine Research: Assures the integrity and sizing of nucleic acids in vaccine workflows with high sensitivity and precision.

Ordering Information

The Agilent 4200 TapeStation System is an advanced solution for high-throughput labs seeking a reliable, scalable, and automated nucleic acid QC platform. Whether for NGS, biobank, or molecular biology workflows, the 4200 delivers trusted performance, flexible throughput, and sustainability—all with minimal hands-on effort.