Thermo Scientific™ Gentamicin sulphate

Thermo Scientific Gentamicin Sulphate is a potent aminoglycoside antibiotic widely used in laboratory research and cell culture applications. This compound is highly effective against a broad range of gram-positive and gram-negative bacteria, making it an essential tool for contamination prevention and microbial inhibition in scientific and industrial applications.

Key Properties:

• Synonyms:
  • NMD Inhibitor II
  • Garamycin
  • Gentamicin Sulphate Salt
  • Gentiomycin C
• Physical Appearance:
  White to yellow powder.
• Melting Point:
  218–237°C
• Storage Temperature:
  Store in a refrigerator to maintain stability and efficacy.
• Molecular Information:
  • MDL Number: MFCD00270181
  • CAS Number: 1405-41-0

Specifications:

• Infrared Spectrum:
  Conforms to the reference standard.
• Assay (Potency):
  ≥590 µg/mg (on a dried basis) ensures high purity and efficacy.
• Loss on Drying:
  ≤18.0% (under vacuum at 110°C for 3 hours), maintaining quality and preventing degradation.
• Sulfated Ash:
  ≤1.0% ensures minimal inorganic impurities.
• pH Range:
  3.5 to 5.5 (at a concentration of 4% in water), ensuring compatibility with various biological systems.
• Specific Optical Rotation:
  Conforms (on a dried basis), demonstrating its consistency and quality.

Applications:

1. Cell Culture and Microbiology:
   • Used to prevent bacterial contamination in mammalian and microbial cell cultures.
   • Effective against gram-positive and gram-negative bacteria in tissue culture systems.
2. Molecular Biology Research:
   • Maintains sterile conditions in cloning and expression studies.
   • Commonly used in genetic research involving bacteria.
3. Pharmaceutical Research:
   • Investigates antibiotic resistance mechanisms.
   • Evaluates the effects of aminoglycosides on cellular processes.
4. Industrial Applications:
   • Used in large-scale fermentation to protect cultures from bacterial contamination.
   • Integral in quality control testing in biomanufacturing environments.

Advantages:

• High Potency: Offers ≥590 µg/mg activity, ensuring effective bacterial inhibition.
• Broad Spectrum: Effective against a wide variety of bacterial species.
• Reliable Stability: Stored at refrigeration temperatures to retain full activity.
• High Purity: Low sulfated ash content and strict quality control ensure consistency.

Packaging:

• Available Sizes:
  • 1 g (Catalog No.: ACRO455310010)
  • 5 g (Catalog No.: ACRO455310050)
  • 25 g (Catalog No.: ACRO455310250)
• Pack Type: Glass bottles for secure storage and easy handling.

Storage and Handling:

• Storage Conditions:
  • Store refrigerated to maintain chemical stability.
• Handling Precautions:
  • Use personal protective equipment during handling.
  • Avoid inhalation and skin contact.

Thermo Scientific Gentamicin Sulphate is an essential reagent for researchers and professionals working in microbiology, cell culture, and pharmaceutical research. Its high potency, broad-spectrum activity, and reliable quality make it a preferred choice for ensuring the sterility and integrity of experimental systems.