Thermo Scientific™ Remel™ Agglutinating Sera, Salmonella O/Vi Polyvalent

The Remel™ Agglutinating Sera, Salmonella O/Vi Polyvalent is a serological tool designed for the identification of somatic (O) and Vi antigens in Salmonella strains. This product is ideal for diagnostic and epidemiological purposes, providing a rapid, reliable method for serotyping Salmonella isolates.

Key Features

1. Rapid Results:
   • Provides visible agglutination results in 1 minute, enabling quick decision-making.
2. Ready-to-Use Reagents:
   • Comes as liquid reagents in 2 mL vials, pre-preserved with 0.5% phenol or 0.1% sodium azide for ease of use.
3. High Specificity:
   • Antisera are absorbed to remove agglutinins for other Salmonella antigens and paracolon α agglutinin, ensuring precise identification.
4. Serological Identification:
   • Designed for the identification of somatic O/Vi antigens in Salmonella (Groups A-S) using the Kauffmann-White Scheme.
5. Versatility:
   • Can be used in both slide and tube agglutination tests for flexibility in laboratory workflows.
6. Ease of Interpretation:
   • Visible agglutination indicates a positive result, simplifying the diagnostic process.

Applications

1. Clinical Diagnostics:
   • Aids in the identification of Salmonella isolates for patients with suspected bacterial infections.
   • Supports diagnostic workflows to inform treatment options.
2. Food Safety and Epidemiology:
   • Identifies Salmonella spp. in foodborne illness investigations.
   • Useful in outbreak tracking and monitoring the distribution of Salmonella serotypes.
3. Research:
   • Facilitates studies on the classification and serotyping of Salmonella based on O and Vi antigens.

Specifications

Intended Use

• For qualitative slide agglutination screening of Salmonella isolates grown on agar.
• Supports the serological identification of selected Salmonella serotypes.
• Used as part of a diagnostic workflow to aid clinicians in determining treatment options.

Benefits

1. Time-Saving:
   • Produces rapid results compared to traditional methods, improving laboratory efficiency.
2. Accurate and Reliable:
   • High specificity for Salmonella antigens, minimizing cross-reactivity.
3. Versatile Testing:
   • Compatible with slide and tube agglutination methods for various lab settings.
4. Cost-Effective:
   • Reduces delays in identification, enabling faster decision-making in clinical and industrial applications.

How It Works

1. Sample Preparation:
   • Grow Salmonella isolates on agar.
2. Agglutination Testing:
   • Place a small sample on a reaction slide or in a tube.
   • Add Remel™ Agglutinating Sera to the sample.
3. Result Interpretation:
   • Observe visible agglutination within 1 minute:
     • Positive: Agglutination indicates the presence of homologous Salmonella antigens.
     • Negative: No agglutination indicates absence.

Storage and Handling

• Store at 2°C to 8°C to maintain reagent integrity.
• Ensure reagents are used within their specified shelf life.

The Remel™ Agglutinating Sera, Salmonella O/Vi Polyvalent is an essential tool for laboratories involved in the rapid and reliable serotyping of Salmonella isolates. Its ease of use, speed, and specificity make it a valuable resource for clinical diagnostics, food safety, and research applications.

Relevant Standards and References

1. Kauffmann-White Scheme:
   • Classifies Salmonella serotypes based on O and H antigens.
2. Supporting Literature:
   • Edwards, P.R., and Ewing, W.H. (1986). Identification of Enterobacteriaceae.
   • Taylor, J. (1967). The isolation and identification of salmonellae.