Liofilchem® Cefuroxime CXM, Antimicrobial Susceptibility Discs, 5 µg

Liofilchem® Cefuroxime (CXM) Antimicrobial Susceptibility Discs are essential tools in clinical microbiology for determining bacterial susceptibility to cefuroxime, a second-generation cephalosporin antibiotic. These discs are available in concentrations of 1 µg, 5 µg, and 30 µg, facilitating the assessment of bacterial resistance patterns and guiding effective antimicrobial therapy.

Product Overview:

• Manufacturer: Liofilchem S.r.l.
• Product Name: Cefuroxime (CXM) Antimicrobial Susceptibility Discs
• Concentrations Available:
  • 1 µg (Ref. 9232)
  • 5 µg (Ref. 9236)
  • 30 µg (Ref. 9021)
• Packaging: Each concentration is supplied in canisters containing 250 discs. 

Clinical Significance:

Cefuroxime is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli. It is commonly used to treat infections such as respiratory tract infections, skin infections, and urinary tract infections. Determining the susceptibility of bacterial isolates to cefuroxime is crucial for selecting appropriate antimicrobial therapy and mitigating the development of resistance.

Regulatory Standards and Quality Control:

Liofilchem's antimicrobial susceptibility discs are manufactured in compliance with international standards, including those set by the Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST). These organizations provide guidelines for performance standards, interpretative criteria, and quality control procedures to ensure the accuracy and reliability of susceptibility testing.

Quality Control Testing:

To ensure the reliability of cefuroxime susceptibility testing, laboratories should perform quality control using standard reference strains with known susceptibility profiles. The following quality control strains and their expected zone diameter ranges for cefuroxime 30 µg discs are recommended:

Regular testing with these control strains ensures that the test conditions are optimal and that the cefuroxime discs are performing within specified parameters. If the zone diameters obtained for the control strains fall outside the expected ranges, it is essential to investigate potential issues with the testing procedure, reagents, or equipment.

Comparison with Other Brands:

Several manufacturers produce cefuroxime antimicrobial susceptibility discs. A comparison of Liofilchem's discs with those from other brands is as follows:

Advantages of Liofilchem® Cefuroxime Discs:

• Variety of Concentrations: The availability of multiple concentrations (1 µg, 5 µg, and 30 µg) allows for flexibility in testing various bacterial isolates and adherence to different testing guidelines.
• Compliance with International Standards: Manufactured in accordance with CLSI and EUCAST standards, ensuring reliability and accuracy in susceptibility testing.
• Bulk Packaging: Supplied in canisters of 250 discs, which may be more economical and convenient for high-throughput laboratories.

Liofilchem® Cefuroxime Antimicrobial Susceptibility Discs are reliable tools for assessing bacterial susceptibility to cefuroxime. Their compliance with international standards, availability in multiple concentrations, and bulk packaging options make them suitable for various clinical microbiology laboratory needs. Regular quality control testing is essential to maintain the accuracy and reliability of susceptibility results.